Yearly Archive

Yearly Archives: 2014

April 30, 2014 no comments

Drug prices are (unnecessarily) high because R&D is (unnecessarily) inefficient

Let me put it in bold text and a large font, lest there be any misunderstanding of DrugBaron’s position:

 

Healthcare costs are manifestly too high and completely unsustainable in the medium term.  That includes drug prices.

This is not inconsistent with the two recent articles (here, here) on drug pricing, which set out to defend the mechanism by which prices are set for proprietary medicines, for at least two reasons.  Firstly, drugs and medical devices represent a minority (by some estimates as little as 10%) of healthcare spending, so even dramatic falls in drug prices would hardly move the overall budget.  And secondly, approval for the mechanism of setting drug prices does not equate to approval for paying the prices demanded.

 

The open letter to Henry Waxman, berating his ill-conceived intervention on drug pricing, drew (perhaps unsurprisingly), considerable support from the broadly-defined drugs industry and howls of protest from healthcare consumers.

 

The voices of disagreement, though, focused on the actual prices – branding them, probably correctly, as “unaffordable” (among some stronger language) – rather than, as DrugBaron had done, on the mechanism that yielded those prices and the appropriateness of Congressman Waxman’s intervention.

 

Repeating the central point: governments should defend Gilead’s right to charge whatever it wishes for Solvaldi™ while it remains patent protected – simply because that is the contract implicit in the patent.  Without strong patents, there would be much less innovation, to the detriment of us all.

 

But that is not the same thing as saying that governments (or other healthcare providers) should pay what is demanded

That, historically, they have done so is driven primarily by the powerful “entitlement culture” that pervades Western democracies, and grows stronger with each passing decade.  Everyone expects to have access to every possible medical intervention, no matter the cost.

 

Yet, ironically, it is this entitlement culture, and the social and political pressure that results, which underpins the unsustainable cost of healthcare.  Paying high prices (and not just for proprietary drugs) supports a hugely inefficient healthcare market, bloated by public cash spent to satisfy the demands of those who equate inputs with outputs.  It sustains broken R&D strategies within vast, global pharma companies.

 

Refusing to pay for inefficiency is the only way to drive essential reforms.  That may well include refusing to pay what is demanded even for life-saving drugs.   The pressure is building, and the revolution may be nearer than you think.

 

More

More
March 3, 2014 no comments

Medicalizing biomarkers – the sure-fire road to commercial success

Creating new drugs is a process fraught with …

More
January 23, 2014 no comments

Even odds-on favourites can lose: lessons from the Prosensa story

With the details from the DEMAND-III study, the …

More
January 3, 2014 no comments

Never mind how many, feel the sales potential – the Class of 2013 FDA Approvals

With thirty-nine approvals from the FDA, 2012 triggered …

More
December 10, 2013 comments

Monte Carlo models of drug R&D focus attention on cutting costs – Part 1

There is a theme behind many of DrugBaron’s …

More
December 9, 2013 comments

Monte Carlo models of drug R&D focus attention on cutting costs – Part 2 (the caveat!)

“So DrugBaron tells me that drug discovery and …

More
October 24, 2013 comments

Evidence that “pick the winners” is precisely the wrong strategy

The asset-centric platform at Index Ventures is built …

More
October 2, 2013 no comments

PheWAS – the tool that’s revolutionizing drug development that you’ve likely never heard of

Late-stage attrition kills returns on pharma R&D investment.  …

More
September 9, 2013 comments

Asset-centric project financing is AN answer – not THE answer

As In Vivo blog noted last week, asset-centric …

More
September 4, 2013 comments

Platform Technologies – the foundations of big pharma or their nemesis?

It has often been said that one of …

More

Yearly Archive