Yearly Archive

Yearly Archives: 2012

July 24, 2012 no comments

Funxional Screening: The Functional Therapeutics Story

FX125L is a fascinating molecule.  A first-in-class anti-inflammatory agent, targeting a newly discovered pathway promoting the resolution of chronic inflammation, it holds exceptional promise as a first line treatment option in a number of major disease areas, including asthma, COPD and rheumatoid arthritis.

As Boehringer Ingelheim announce the acquisition of the FX125L from Funxional Therapeutics, a Cambridge-based privately-held biotech company founded by DrugBaron in 2005, the story of the discovery and early development of this drug product candidate illustrates some important lessons for drug discovery in the 21st Century – whether in a virtual biotech or a multinational pharma company.

The most important characteristics of FX125L are its intriguing new target and its ideal pharmaceutical properties.  Both depended on a fair slice of luck, but the way in which we loaded the dice in our favour could be applied much more widely.

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July 23, 2012 no comments

Boehringer Ingelheim and Funxional Therapeutics announce acquisition of Funxional’s FX125L and the somatotaxin portfolio to treat inflammation

Ingelheim, Germany and Cambridge, UK – 23 July …

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July 16, 2012 no comments

Autophagy: The Higgs Particle of Biology?

With all the excitement surrounding the discovery of …

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